Humira An Overview of FDAApproved Uses and Mechanism
Hello and welcome to quot;TutorialScriptquot;, presentedby ugs . Todaythe first of three presentations,we are ing Humira, a mediionthe class of ugs known as tumor necrosis factor,or TNF blockers. Humira, known by the generic name of adalimumab,is approved by the FDA for treatment of adults with moderate to severe rheumatoid arthritis,and for usemoderate to severe Crohn's diseasepatients who have not had successwith other therapies. Humira is also approved for treatment of otherimmunemediated conditions, including plaque psoriasis, psoriatic arthritis, juvenile idiopathicarthritis, and ankylosing spondylitis.
Normally, the immune system can defend thebody from harmful effects. Inflammation is a normal process used by the body for repairof injury or illness. However,autoimmune disease, healthy tissues are attackedthebody. Rheumatoid arthritis and Crohn's disease are considered autoimmune diseases. TNF is a protein normally foundthe bodythat promotes the normal defense mechanism of inflammation. However,rheumatoid arthritisand Crohn's disease, TNF levels are too high, and this leads to the inflammation,pain, and fever that are commonly seen with these diseases. Additionally,rheumatoidarthritis, there is tenderness and swelling
of the joints, andCrohn's disease thereis abdominal pain and diarrhea. Humira is a synthetic antibody and works bybinding and blocking this TNF protein. By blocking this protein, Humira helps to keepthe protein from attacking healthy cells, and reduces the inflammation, pain and otherdestructive effects seen on the joints andthe intestine. Although Humira is an injection that is givenunder the skin, most patients, or their caregivers can be taught to give the injection at home,so it can be very convenient for the patient. Doses are variable based upon the needs ofthe patient, but usually injections are given
only once every other week. Humira is supplieda singleuse prefilledglass syringe, which makes it easier for the patient to give their own doses. Humira shouldbe storedthe refrigerator until needed. Thank you for joining us at ugs fora brief of Humira. Please refer to our patient and professional information,ug interaction checker, and additional tools on ugs . Patients with a concern about the use of Humirashould consult with their health care provider. Visit ugs Humira for more information
Information on Humira the Brand Name Form of Adalimumab
Humira, the brand name form of adalimumab,is a prescription mediion used to treat certain kinds of arthritis, ankylosing spondylitis,Crohn's disease, plaque psoriasis, and ulcerative colitisadults and chilen. Humira belongsto a group of ugs called tumor necrosis factor blockers, which help reduce inflammation.This mediion comesan injectable form and is injected just under the skin usuallyonce every other week. Common side effects of Humira include reaction at the injectionsite, sinus infections, and headaches.